• Chao-Hsien Chen, Ph.D.
  • Associate Professor & Director
    Department of Medical Laboratory Science and Biotechnology, College of Health Care, China Medical University
  • Phone: (886)- 4-2205-3366 ext. 7205
  • E-mail:chchen@mail.cmu.edu.tw


  • Ph.D. in Institute of Molecular Biology, National Chung Hsin University, Taichung, Taiwan.
  • MS in Clinical Laboratory Sciences, College of Natural Science, Michigan State University, East Lansing, Michigan, USA
  • BS in Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan.


  • Director and Associate Professor, Department of Medical Laboratory Science and Biotechnology, China Medical University.
  • Associate Professor, Department of Chemical and Materials Engineering, National Chin-Yi University of Technology

Research Interests

  • The Resistance of Microorganisms and its Surveillance
  • Physiology of Gene Amplification and its Regulation

Journal Papers

  • Lan YC1, Su MC, Chen CH, Huang SH, Chen WL, Tien N, Lin CW., Epidemiology of pandemic influenza A/H1N1 virus during 2009-2010 in Taiwan. Virus Res. 2013 Oct;177(1):46-54.
  • Chen CH1, Huang CC, Chung TC, Hu RM, Huang YW, Yang TC, Contribution of resistance-nodulation-division efflux pump operon smeU1-V-W-U2-X to multidrug resistance of Stenotrophomonas maltophilia. Antimicrob Agents Chemother. 2011 Dec;55(12):5826-33.
  • Chen CH1, Chang CP, Wu FY, Liu CL, Peng CT, Lin CW., Prevalence of human herpesvirus 8 DNA in peripheral blood mononuclear cells of acute and chronic leukemia patients in Taiwan. FEMS Immunol Med Microbiol. 2011 Apr;61(3):356-8.
  • Kuan YC, Kao CH, Chen CH, Chen CC, Hu HY, Hsu WH., Biochemical characterization of a novel lysine racemase from Proteus mirabilis BCRC10725. Proc. Biochem. 2011; 46:1914-20
  • Lin CF1, Hsu SK, Chen CH, Huang JR, Lo HH., Genotypic detection and molecular epidemiology of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in a regional hospital in central Taiwan. J Med Microbiol. 2010 Jun;59(Pt 6):665-71.
  • Shen GH1, Hung CH, Hu ST, Wu BD, Lin CF, Chen CH, Wu KM, Chen JH. Combining polymerase chain reaction restriction enzyme analysis with phenotypic characters for mycobacteria identification in Taiwan. Int J Tuberc Lung Dis. 2009 Apr;13(4):472-9.
  • Shen GH1, Chen CH, Hung CH, Wu KM, Lin CF, Sun YW, Chen JH., Combining the Capilia TB assay with smear morphology for the identification of Mycobacterium tuberculosis complex. Int J Tuberc Lung Dis. 2009 Mar;13(3):371-6.
  • Chen S-O), T-J Chang, G. Stone), Chen CH, JJ Liu*, Programmed Cell Death Induced by Japanese Encephalitis Virus YL Vaccine Strain or its Recombinant Envelope Protein in Varied Cultured Cell, INTERVIROLOGY, 2006 Oct, (49):346-351.
  • Chen CH, Hui-Yi Hu*, Yen-Ching Cho, Wen-Hwei Hsu, Screening of compactin-resistant microorganisms capable of converting compactin to pravastatin, CURRENT MICROBIOLOGY, 2006 Apr,(53):108-112.
  • Chen CH, Ju Chien Cheng, Yen-Ching Cho, Wen-Hwei Hsu*)*, A gene cluster for the fatty acid catabolism from Pseudonocardia autotrophica BCRC12444, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2005 Apr, 329(329):863-868.
  • Chen CH, Jing-Gung Chung *, Arylamine N-Acetyltransfdrase Activities in Leukocytes Collected from Human, Pigeon, Frog and Rabbit. China medical college journal, 1998 Mar, 7(1):27-36.

Conference Papers

  • Overexpression of Resistance Nodulation Division Afflux Pump SmeVWX Confers to the Multidrug Resistance of Stenotrophomonas maltophilia,台灣微生物學會第二十屆會員大會暨學術研討會,台灣大學醫學院五樓,2010.12.12 ~ 2010.12.12
  • Proteus mirabilis 生物膜基因選殖及其表現,第三屆亞洲大學暨中國醫藥大學生物科技研討會,亞洲大學行政大樓國際會議中心,2010.3.16 ~ 2010.3.16
  • 變形桿菌的生物膜對抗藥性的影響,第二屆中國醫藥大學暨亞洲大學生物科技研討會,中國醫藥大學國際會議廳,2009.3.16 ~ 2009.3.16
  • 台灣中部結核分枝桿菌抗藥性結果趨勢分析,中華民國醫事檢驗學會97年度年會與學術研討會,台大醫院國際會議中心,2008.11.16 ~ 2008.11.16
  • Pyrazinaside Resistance and pncA Genotypic Diversity of Multidrug-resistant Mycobacterium tuberculosis,亞太醫學檢驗科學國際研討會(Asia-Pacific Medical Laboratory Science Forum),台中金典大飯店,2008.2.23 ~ 2008.2.24
  • 變異性重複序列分析結核分枝桿菌菌株,2007研究學習群校級研究成果發表會,南投縣惠蓀林埸,2007.12.1 ~ 2007.12.2
  • The drug resistance rate of Mycobacterium tuberculosis complex in Central Taiwan in 2005-2006,38th Union World Conference on Lung Health,Cape Town, South Africa,2007.11.8 ~ 2007.11.12
  • A novel algorithm for identifing mycobacterium species by rpoB duplex PCR-RFLP with key phenotypic characters,38th Union World Conference on Lung Health,Cape Town, South Africa,2007.11.8 ~ 2007.11.12
  • 台灣西部近五年結核分枝桿菌抗藥性分析,中華民國醫事檢驗學會96年度年會與學術研討會,台北,2007.11.10 ~ 2007.11.11