Laboratory of Virology and Infectious Disease

Kuo-Ching Liu,PhD(劉國慶博士)

Lecturer Department of Medical Laboratory Science and Biotechnology, China Medical University
Phone: 886-4-22053366 ext. 7206
Fax: 886-4-22057414
Office: 14 F, Li-Fu Teaching Building
Mailing Address: Department of Medical Laboratory Science and Biotechnology, China Medical University
91, Hsueh-Shih Rd., Taichung, Taiwan 40402, R.O.C.
40402 台中市北區學士路91號 中國醫藥大學醫學檢驗生物技術學系


Institution Nation Department/Program Degree
National Chung Hsing University Taiwan, ROC Graduate Institute of Biotechnology Ph.D.


Current Position

Institution Department/Program Position Duration
China Medical University Department of Medical Laboratory Science and Biotechnology Assistant professor From 2011 to now



  • Screening for the anticancer herbals



  • Excellent university tutor awards at China Medical University, Nov 2011



Publications in Last Five Years

  1. Weng SW, Hsu SC, Liu HC, Ji BC, Lien JC, Yu FS, Liu KC, Lai KC, Lin JP, Chung  JG. Gallic acid induces DNA damage and inhibits DNA repair-associated protein expression in human oral cancer SCC-4 cells. Anticancer Res. 2015;35(4):2077-84. (SCI)
  2. J-H Chiang, J-S Yang, C-C Lu, M-J Hour, K-C Liu, J-H Lin, T-H Lee1, and J-G
  3. Chung. Effect of DNA damage response by quinazolinone analogue HMJ-38 on human
  4. umbilical vein endothelial cells: Evidence for gH2A.X and DNA-PK- dependent pathway.
  5. Hum Exp Toxicol. 2014;33(6):590-601. (SCI)
  6. Liu KC, Yen CY, Wu RS, Yang JS, Lu HF, Lu KW, Lo C, Chen HY, Tang NY, Wu CC, Chung JG. The roles of endoplasmic reticulum stress and mitochondrial apoptotic signaling pathway in quercetin-mediated cell death of human prostate cancer PC-3 cells. Environ Toxicol. 2014;29(4):428-39. (SCI)
  7. Ni WY, Lu HF, Hsu SC, Hsiao YP, Liu KC, Liu JY, Ji BC, Hsueh SC, Hung FM, Shang HS, Chung JG. Phenethyl isothiocyanate inhibits in vivo growth of subcutaneous xenograft tumors of human malignant melanoma A375.S2 cells.  In Vivo. 2014;28(5):891-4. (SCI)
  8. Chan YK, Huang DH, Liu KC, Chen RT, Jiang X. An automatic Indirect
  9. immunofluorescence cell segmentation system. Math Prob Engineer. 2014;2014:501206. (SCI)
  10. Wu KC, Yang ST, Hsu SC, Chiang JH, Hsia TC, Yang JS, Liu KC, Wu RS, Chung JG.     Propofol induces DNA damage in mouse leukemic monocyte macrophage RAW264.7 cells. Oncol Rep. 2013;30(5):2304-10. (SCI)
  11. Liu KC, Ho HC, Huang AC, Ji BC, Lin HY, Chueh FS, Yang JS, Lu CC, Chiang JH, Meng M, Chung JG. Gallic acid provokes DNA damage and suppresses DNA repair gene expression in human prostate cancer PC-3 cells. Environ Toxicol. 2013;28(10):579-87. (SCI)
  12. Wu RS, Liu KC, Tang NY, Chung HK, Ip SW, Yang JS, Chung JG. cDNA microarray analysis of the gene expression of murine leukemia RAW 264.7 cells after exposure to propofol. Environ Toxicol. 2013;28(8):471-8. (SCI)
  13. Fan MJ, Lin YC, Shih HD, Yang JS, Liu KC, Yang ST, Lin CY, Wu RS, Yu CS, Ko YC, Chung JG. Crude extracts of Agaricus brasiliensis induce apoptosis in human oral cancer CAL 27 cells through a mitochondria-dependent pathway. In Vivo. 2011;25(3):355-66. (SCI)
  14. Wu YY, Chen JH, Kao JT, Liu KC, Lai CH, Wang YM, Hsieh CT, Tzen JT, Hsu PN. Expression of CD25(high) regulatory T cells and PD-1 in gastric infiltrating CD4(+) T lymphocytes in patients with Helicobacter pylori infection. Clin Vaccine Immunol. 2011;18(7):1198-201. (SCI)
  15. Liu KC, Huang AC, Wu PP, Lin HY, Chueh FS, Yang JS, Lu CC, Chiang JH, Meng M, Chung JG. Gallic acid suppresses the migration and invasion of PC-3 human prostate cancer cells via inhibition of matrix metalloproteinase-2 and -9 signaling pathways. Oncol Rep. 2011;26(1):177-84. (SCI)
  16. Wu PP, Chung HW, Liu KC, Wu RS, Yang JS, Tang NY, Lo C, Hsia TC, Yu CC, Chueh FS, Lin SS, Chung JG. Diallyl sulfide induces cell cycle arrest and apoptosis in HeLa human cervical cancer cells through the p53, caspase- and mitochondria-dependent pathways. Int J Oncol. 2011;38(6):1605-13. (SCI)
  17. Wang YM, Lu TL, Hsu PN, Tang CH, Chen JH, Liu KC, Kao JT, Tzen JT, Wu YY. Ribosome inactivating protein B-chain induces osteoclast differentiation from monocyte/macrophage lineage precursor cells. Bone. 2011;48(6):1336-45. (SCI)
  18. Wu PP, Liu KC, Huang WW, Chueh FS, Ko YC, Chiu TH, Lin JP, Kuo JH, Yang JS, Chung JG. Diallyl trisulfide (DATS) inhibits mouse colon tumor in mouse CT-26 cells allograft model in vivo. Phytomedicine. 2011;18(8-9):672-6. (SCI)
  19. Liu KC, Huang YT, Wu PP, Ji BC, Yang JS, Yang JL, Chiu TH, Chueh FS, Chung JG. The roles of AIF and Endo G in the apoptotic effects of benzyl isothiocyanate on DU 145 human prostate cancer cells via the mitochondrial signaling pathway. Int J Oncol. 2011;38(3):787-96. (SCI)
  20. Wu PP, Liu KC, Huang WW, Ma CY, Lin H, Yang JS, Chung JG. Triptolide induces apoptosis in human adrenal cancer NCI-H295 cells through a mitochondrial-dependent pathway. Oncol Rep. 2011;25(2):551-7. (SCI)



Undergraduate Program

  • Introduction to Medical Biotechnology Research Methods
  • Human Genetics
  • Diagnostic Cytology & Histopathological Techniques
  • Diagnostic Cytology & Histopathological Techniques Laboratory
  • Cell Culture
  • Clinical Parasitology
  • Clinical Microscopy
  • Clinical Microscopy Laboratory
  • Geriatrics and Laboratory Medicine
  • Molecular Biology and Biotechnology Laboratory
  • Clinical Serology and Immunology
  • Clinical Serology and Immunology Laboratory
  • Laboratory Genetics
  • New Trends in Clinical Microscopy & Pathology
  • Interpretation for Clinical Laboratory Data (PBL)
  • PBL (School of Medicine)
  • PBL (School of Chinese Medicine)
  • PBL (School of Dentistry)
  • General Biology (C) (Department of Health Services Administration)
  • General Biology (C) (School of Nursing)
  • General Biology Lab (B) (School of Medicine)
  • General Biology Lab (B) (School of Dentistry)
  • General Biology Lab (B) (School of Chinese Medicine)

Postgraduate Program

  • Molecular & Cellular biology (I)
  • Special Topics on Signal Transduction & Human Disease